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To generate sufficient quantities of ROS and RNS quickly, these cells require rapid flux through the PPP to produce sufficient amounts of NADPH to enable superoxide formation from oxygen by the action of NADPH oxidase (NOX), and nitric oxide (NO) formation from arginine by inducible nitric oxide synthase (iNOS) ( Figure 1A-2 )

Replenishing electrolytes also helps maintain proper muscle and nerve function, which can reduce the sluggish, off feeling that often accompanies a hangover

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